14th Congress on Alternatives to Animal Testing – Linz 2008
& 11th Annual Meeting of MEGAT – Middle European Society for Alternative Methods to Animal Testing
September 28th-30th 2007, Linz, Austria
Program Linz 2007
Friday, September 28th, 2007
13.00-13.15
Welcome speeches
13.15-13.30
Horst Spielmann, D-Berlin
More than a decade of congresses on alternatives to animal testing in Linz - what has been achieved?
EU-chemicals policy (REACH) & endocrine disruptors
chair: Spielmann Horst, D-Berlin
13.30-14.00
Hartung Thomas, I-Ispra
The status of the implementation of REACH
14.00-14.25
Vogel Richard, D-Berlin
The need for improvement of the Integrated Testing Strategy for reproductive toxicity under REACH
14.25-14.50
Benisch Peter A., NL-Amsterdam
REACH & endocrine disruptors - the current situation
14.50-15.10
Kandarova Helena, USA-Ashland
Increased Sensitivity of the EpiDerm Skin Irritation Protocol Evaluated in the ECVAM Skin Irritation Validation Study
15.10-15.25
José Cotovio, FR-Aulnay Sous Bois
In Vitro 3-D human reconstructed models for the evaluation of ocular and skin irritation. Corneal epithelial model HCE-optimized protocol and epidermal model EPISKIN-ECVAM validated protocol applied to a serie of cosmetic ingredients
15.25-15.40
Gladys Ouédraogo, FR-Aulnay Sous Bois
Genotoxicity: A new and promising use of in vitro models
15.40-16.00
Rogiers Vera, B-Brussels
ecopa’s EU FP7 project START-UP: Scientific and technological issues in 3Rs alternatives research in the process of drug development and Union politics
16.00-16.20
Wimmer Christian, B-Brussels
EC funding of alternative testing strategies
16.20-17.00
Coffee break and posters
Poster session
17.00-18.30
Postersession I
Survey of the posters with presence of the authors
Society ALTEX Edition
18.30-19.30
Society ALTEX Edition - Annual General Assembly
Welcome Reception
19.30
Welcome Reception (at the congress venue, next to the posters)
Saturday, September 29th, 2007
Ecotoxicology
chair: Benisch Peter A., NL-Amsterdam
08.30-09.00
Ryan Gavin, IRL-Dublin
Development of a functional in vitro bioassay for the marine biotoxin azaspiracid (AZA) using human colonic epithelial cells
09.00-09.20
Schirmer Kristin, D-Leipzig
Towards replacing or refining fish tests in chemical regulation and effluent testing – strategies to advance fish cell lines and embryos as alternatives
Good Cell Culture Practice
chair: Gstraunthaler Gerhard, A-Innsbruck
09.20.09.25
Gstraunthaler Gerhard, A-Innsbruck
Introduction
09.25-09.40
Leist Marcel, D-Konstanz
The value of the BV-2 cell line as model for primary microglia
09.40-09.55
Jennings Paul, A-Innsbruck
Standardisation of cell culture techniques: a prerequisite to effective multi laboratory comparison of microarray data
09.55-10.10
Bahramsoltani Mahtab, D-Berlin
Establishment of realistic in vitro models of angiogenesis: how to make the right choice
10.10-10.50
Coffee break and posters
Nanotoxicology
chair: Pfaller Walter, A-Innsbruck
10.50-11.05
Taylor Katy, UK-London
In vitro techniques and nanotoxicity - the way forward
11.05-11.20
Lenz Anke-Gabriele, D-Neuherberg
Proinflammatory response in human alveolar epithelial cells exposed to ultrafine zinc oxide (ZnO) particles at the air-liquid interface (ALI)
11.20-11.35
Rothen-Rutishauser Barbara, CH-Bern
A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles
11.35-11.50
Vankoningsloo Sébastien, B-Namur
Nanotoxico: In vitro model development for nanomaterial toxicity assessment on human health
Evidence based toxicology
chair: Rogiers Vera, B-Brussels
11.50-12.10
Hoffmann Sebastian, I-Ispra
Toward an evidence-based toxicology
12.10-12.25
Runge Dieter, D-Schwerin
A human hepatocyte long-term culture system serves as a drug testing alternative to animal models: Results of metabolic assays and electron microscopy
12.25-14.00
Lunch
Ethical and legal aspects
chair: Franz P. Gruber, CH-Zurich
14.00-14.20
Leist Marcel, D-Konstanz
Judging the value of alternative methods
14.20-14.35
Kolar Roman, D-Neubiberg
Survey of the German Animal Welfare Federation concerning the work of ethics committees and licensing authorities for animal experiments
14.35-14.50
Knight Andrew, UK-London
Animal experiments scrutinised: systematic reviews demonstrate poor human clinical and toxicological utility
14.50-15.05
Ruhdel Irmela, D-Neubiberg
Revision of Directive 86/609: Demands from the animal welfare point of view
15.05-15.20
Reid Kirsty, B-Brussels
Animal welfare and the revision of EU legislation on Plant Protection Products
15.20-15.35
Balluch Martin, A-Vienna
Trial for personhood of a chimp
15.35-16.15
Coffee break and posters
Poster session
16.15-18.15
Postersession II
Survey of the posters with presence of the authors
MEGAT
18.15-19.15
MEGAT - Annual General Assembly
Social Evening
19.30
Departure for the Social Evening
20.00
Social evening - Award ceremonies
- Doerenkamp-Zbinden-Award,
- Doerenkamp-Zbinden Foundation Honour Medals,
- ALTEX Publication Award,
- Bo Holmstedt Memorial Fund Poster Award
- Poster Award Linz 2007,
- PromoCell thesis award Linz 2007
Sunday, September 30th, 2007
Computer assisted procedures
chair: Jennigs Paul, A-Innsbruck
09.00-09.15
Langton Kate, UK-Leeds
Derek for Windows: Conforming to the OECD principles for (Q)SAR validation
09.15-09.30
Waechter Thomas, D-Dresden
Knowledge based search - A new search machine for knowledge intense domains
09.30-09.45
Motzkus Nicole, D-Erlangen
New animal model for objective pain research: Non-invasive functional imaging in anesthetized animals by BOLD fMRI
09.45-10.15
Coffee break and posters
7th cosmetics amendment
chair: Kolar Roman, D-Neubiberg
10.15-10.30
Manfred Liebsch, D-Berlin
ECVAM Photopotency Feasibility Study: In Vitro Skin Model Phototoxicity Test for Determination Phototoxic Potency of Topical Phototoxins
10.30-10.45
Ruwiedel Karsten, D-Düsseldorf
COLIPA Skin Metabolism Project - towards the inclusion of appropriate metabolism in in vitro alternatives for skin sensitisation and genotoxicity
10.45-11.00
Kandarova Helena, USA-Ashland
In Vitro Skin Corrosion Test: Reproducibility Over Time and Optimized Methodology for Testing Chemicals Interfering with the MTT Endpoint
11.00-11.15
Szameit Sandra, A-Seibersdorf
Discrimination of contact allergens and irritants employing the ARC immune toxicity chip
11.15-11.30
Wanner Reinhard, D-Berlin
LCSA, Loose-fit Coculture-based Sensitization Assay
11.30-11.45
Heisler Eckhard, D-Krefeld
When in vitro toxicology meets a global player: Research and Development of Degussa’s Super Absorbing Polymers are accompanied by alternative methods in toxicology
Target organ toxicity
chair: Hartung Thomas, I-Ispra
11.45-12.00
Seiler Andrea, D-Berlin
The new German BMBF joint project on the development of predictive in vitro tests for developmental neurotoxicity testing
12.00-12.15
Leist Marcel, D-Konstanz
A human neuronal model system with a potential to substitute primary cultures
12.15-12.30
Fritsche Ellen, D-Düsseldorf
News from the neurosphere front
12.30-12.45
Albus Klaus, D-Berlin
In vitro alternatives to animal models for screening and evaluation of anticonvulsive compounds
12.45-13.00
Brigitta Loretz, D-Saarbrücken
Pulmonary cell culture models to study safety and efficacy of innovative aerosol medicines
13.00-13.15
Sewald Katherina, D-Hannover
Mouse Precision Cut Lung Slices (PCLS) as Alternative for in vivo Respiratory Toxicology Testing: Focus on Immune Modulating LPS and Allergens
13.15-13.30
Telang Nitin, USA-New York
Novel cell culture model for prevention of estrogen receptor negative, chemotherapy-resistant breast cancer: an alternative approach for animal experimentation
13.30-13.45
Balogh Lajos, H-Budapest
3Rs in the field of radiopharmaceutical research and development
13.45
Closing remarks - End of the 14th congress
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