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Approved continuing education by Swiss association of cantonal veterinarians.

September 19^th-21^st 2008, Linz, Austria

Program Linz 2008 (download)

Friday, September 19^th 2008
13.00-13.10	Welcome address
3R updates
13.10-13.40	KOËTER HERMAN B.W.M., I-Parma The use of animals in food and feed safety assessment: Interesting developments
13.40-14.10	HENDRIKSEN COENRAAD, NL-Bilthoven An up-date of Three Rs progress in the area of vaccine quality control
Legal and ethical questions - part I
14.10-14.25	TAYLOR KATY, UK-London Making the EU Directive 86/609/EEC work for animals
14.25-14.40	SCHIFFELERS MARIE-JEANNE, NL-Utrecht Regulatory animal testing: factors stimulating or obstructing the adoption of 3R methods in the regulatory process
14.40-15.10	Coffee break and posters
Legal and ethical questions - part II: panel discussion
15.10-17.00	Embryonic or adult stem cells: scientific and ethical considerations panellists: BREMER SUSANNE, Joint Research Centre of the EU, I-Ispra BRUCE DONALD, Edinethics Ltd, UK-Edinburgh GSTRAUNTHALER GERHARD, Innsbruck Medical University, A-Innsbruck, and zet, A-Linz KADEREIT SUZANNE, University of Konstanz, D-Konstanz SPIELMANN HORST, Freie Universität Berlin, D-Berlin, and Federal Institute for Risk Assessment, D-Berlin moderator: GRUBER FRANZ P., Society ALTEX Edition, CH-Kuesnacht, and Doerenkamp-Zbinden Foundation, CH-Kuesnacht
17.00-18.30	Poster session I with coffee Survey of the posters with presence of the authors
18.30-19.30	Society ALTEX Edition - Annual General Assembly
19.30	Welcome Reception (at the congress venue, next to the posters)

Saturday, September 20^th 2008
New developments in alternative testing methods
09.00-09.15	BUREK CHRISTOF, D-Wuerzburg Predict-IV: Developing novel alternative testing strategies for use in pharmaceutical discovery and development
09.15-09.30	DONG MIN, CH-Muttenz High-content cellular imaging approach for in vitro toxicology
09.30-09.45	BOCK UDO, D-Saarbruecken Validation of an ex vivo human cervical tissue model for the local delivery of nucleic acid drugs
10.00-10.15	PAUWELS MARLEEN, B-Brussels The incorporation of 3R alternatives in the safety evaluation of cosmetic ingredients by the SCC(NF)P
Alternative testing methods for toxicity to reproduction and development
10.15-10.30	VOGEL RICHARD, D-Berlin Perspectives for alternative methods to animal testing in the field of reproductive toxicology
10.30-10.45	ROCKEL THOMAS DINO, D-Duesseldorf The three dimensional human neurosphere model identifies developmental neurotoxicants
10.45-11.15	Coffee break and posters

Computer-assisted procedures
11.15-11.45	WORTH ANDREW, I-Ispra In silico estimation tools developed by the Joint Research Centre in support of chemicals legislation
11.45-12.05	SIMON-HETTICH BRIGITTE, D-Darmstadt Use of computer-assisted models for the prediction of toxic effects of chemical substances
12.05-12.25	STERNBERG MICHAEL J.E., UK-London A logic-based approach for quantitative toxicology prediction
12.25-12.45	VEDANI ANGELO, CH-Basel VirtualToxLab — In silico prediction of the toxic (endocrine-disrupting) potential of drugs and chemicals
12.45-14.15	Lunch (business lunch to be served at the congress venue)

Skin models as alternatives to animal testing
14.15-14.30	KANDÁROVÁ HELENA, USA-Ashland In vitro topical toxicity testing in line with requirements of EU and US regulators: reconstructed human tissue models
14.30-14.45	LIEBSCH MANFRED, D-Berlin Follow-up validation of the modified EpiDerm Skin Irritation Test (SIT): results of a multi-centre study of twenty reference test substances
14.45-15.00	CURREN RODGER D., USA-Gaithersburg Advantages and difficulties in using 3-Dimensional human skin models in toxicology and efficacy studies
15.00-15.15	GUEST ROBERT, UK-Derbyshire An initial evaluation of the CellSystems EST-1000 reconstructed human skin model for distinguishing R34 and R35 corrosives in vitro
15.15-15.30	SCHROEDER KLAUS RUDOLF, D-Duesseldorf The Application of the Phenion® Full Thickness Skin Model as an Alternative Test to predict Toxic Effects
15.30-15.45	ALÉPÉE NATHALIE, F-Aulnay Sous Bois Reconstructed Human Epidermis (RHE): an in vitro skin irritation model for full replacement of the Draize Test
15.45-16.00	COTOVIO JOSÉ, F-Aulnay Sous Bois The use of the SkinEthic human corneal epithelial (HCE) model to predict ocular irritancy: optimized 1H/16H protocol applied to a large set of 400 industrial chemicals
16.00-16.15	DE BRUGEROLLE ANNE, F-Nice SkinEthic Laboratories, a validated choice of in vitro alternative methods to the animal use for skin corrosion and irritation and other selected choices for eye irritation and skin pigmentation
16.15-18.15	Poster session II with coffee Survey of the posters with presence of the authors
18.15-19.15	MEGAT - Annual General Assembly
19.30	Departure for the Social Evening
20.00	Social evening - Award ceremonies

Sunday, September 21^st 2008
Good Cell Culture Practice
09.00-09.10	GSTRAUNTHALER GERHARD, A-Innsbruck Alternatives to the use of fetal bovine serum (FBS): recent strategies to reduce or replace FBS in cell and tissue culture
09.10-09.25	RAUCH CAROLINE, A-Innsbruck Alternatives to the use of fetal bovine serum: platelet lysates as serum replacement in cell and tissue culture
09.25-09.40	LINDL TONI, D-Muenchen New developments in commercial supply of serum-free media
09.40-09.50	BRUNNER DANIEL, A-Linz Serum-free cell culture: the serum-free media interactive online database
Gentechnology & animal experiments / transgenic animals
09.50-10.05	TELANG NITIN, USA-New York Epithelial cell lines for carcinogenesis and chemoprevention: an alternative to complement genetically engineered mouse models
10.05-10.20	TAYLOR KATY, UK-London Reporting 3Rs parameters in European scientific research papers
10.20-10.35	KOLAR ROMAN, D-Neubiberg Animal testing of genetically modified food and feed: can it be justified?
10.35-11.00	Coffee break and posters

Nanotoxicology / Nanobiotechnology
11.00-11.15	SAUER URSULA G., D-Neubiberg Animal experiments and non-animal methods in nanomedicine and nanotechnology – the results of a critical literature survey from the point of view of animal welfare
11.15-11.30	PURZNER MARIA, A-Vienna Nanotoxicology and Alternative Testing Methods – development, chances and needs on OECD and EU level
11.30-11.45	ERTL PETER, A-Vienna Lab-on-a-chip: A Novel Approach to Monitor Nanotoxicology
11.45-12.00	LENZ ANKE-GABRIELE, D- Neuherberg Reduction of animal testing by development of a novel exposure chamber to expose cells to nanoparticles at the air-liquid interface
12.00-12.15	SPIELMANN HORST, D-Berlin Toxicological Evaluation of Nanomaterials in Cosmetic Products
12.15-13.00	Lunch (business lunch to be served at the congress venue)

Free communications
13.00-13.15	GRUNE BARBARA, D-Berlin Go3R – the knowledge-based search engine for information on animal testing alternatives
In vitro toxicology
13.15-13.25	BLAAUBOER BAS J., NL-Utrecht Biokinetic considerations in in vitro toxicology
13.25-13.40	HUANG SONG, CH-Geneva MucilAir: A Novel Human 3D Airway Epithelium Model for Acute or Long Term Toxicity Testing of Chemicals
13.55-14.10	SEWALD KATHERINA, D-Hannover Respiratory toxicology and immunetoxicology in precision cut lung slices (PCLS)
14.10-14.25	HARTUNG THOMAS, I-ISPRA Food for thought on the future of toxicology
14.25	Closing remarks - end of the 15th congress

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