15th Congress on Alternatives to Animal Testing – Linz 2008
& 12th Annual Meeting of MEGAT – Middle European Society for Alternative Methods to Animal Testing
Approved continuing education by Swiss association of cantonal veterinarians.
September 19th-21st 2008, Linz, Austria
Poster (download)
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Human HepaRG® hepatocytes for the detection of toxic metabolic pathways |
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IL-1α release quantification in culture media: how to ensure standardization? |
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In vitro skin irritation assessment of colored and colorant-like chemicals using the ECVAM validated EpiSkinTM assay: the need of appropriate and relevant controls |
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In vitro model for evaluation of Zineb induced oxidative stress, immunsupression and apoptosis |
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Protective effects of herbal cosmetic ingredients assessed in cell and tissue cultures and in human studies |
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A combined assay measuring binding and enzymatic activity allows in vitro detection of tetanus toxicity in vaccines |
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Potency testing of inactivated rabies vaccines for veterinary use: correlation of results between mouse challenge test and serological assay |
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The use of precision cut lung slices to assess nanoparticle mediated toxicity |
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An epithelial airway model to study the effects of gold nanoparticles deposited at the air-liquid interface |
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Towards a European Science without Animal Experiments |
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In vitro acute skin irritancy of 184 cosmetic ingredients using the validated EPISKIN model protocol |
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Optimized 1H/16H SkinEthic human corneal epithelial (HCE) protocol to predict ocular irritancy: application to a large set of 400 industrial chemicals |
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Challenging the legal basis of the rodent carcinogenicity test in UK |
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Towards a standardized trans-epithelial electrical resistance measurement on in vitro cutaneous and ocular reconstructed models |
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Growth of squamous carcinoma cells under the influence of chemotherapeutic agents |
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Correction of surface tension induced refraction artefacts at the meniscus interface in multiwell plates |
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Primary porcine alveolar epithelial cells (pAEpC) as a model for drug permeability assays |
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The antiproliferative activity of the Holocene grain wash out can be enhanced by HulFN-Alpha N3 but not with the rHulFN-Alpha 2 |
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Cell-growth promoting fractions originated from bovine blood clot in combination with the porcine ocular fluid |
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In vitro study of the toxicity induced by Nickel and Cobalt particles on human lung cells |
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Characterisation of a new human renal proximal tubular cell line (RPTEC/TERT1), generated by the introduction of telomerase activity |
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One step further towards computer assisted simulation of percutaneous absorption to avoid animal experiments – the combination of experiment and simulation effectively helps to identify new important parameters |
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Drug metabolizing enzyme activity in human in vitro dermal (EpiDerm™) and airway (EpiAirway™) epithelial models |
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Healing of dermal wounds in the EpiDerm-FT™ in vitro human skin model |
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Development of a predictive in vitro test module for developmental neurotoxicity testing using mouse embryonic stem cells |
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The reference laboratory concept in the United States: Successfully combining in vitro testing services and an education program in a non-profit Institute |
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The Hen`s Egg Testing on the Chorioallantoic Membrane – a model for multiple purposes |
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A new human hepatocyte cell line as a vantage point for a new generation of organoid liver test systems? |
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Alternative endpoints in the LLNA in order to reduce false positive results |
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Alternatives across Latin America: catalysing change in the curriculum |
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Three’s a crowd: the 1R of replacement for education and training |
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Phototoxicity of essential oils intended for cosmetic use |
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Nanotoxicity: application of atomic force microscopy and novel nanoparticle measurement technology |
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Towards an in vitro model for xenobiotic passage at the materno-fetal interface based on permanent cell lines |
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The beginning of the end for chimpanzee experiments? |
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Non-animal methodologies within biomedical research and toxicity testing |
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In vitro differentiation of skin sensitizers by cell signaling pathways |
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Functional assays are mandatory for a correct prediction of immunosuppressant properties of compounds in vitro |
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Generation of functional astrocytes from embryonic stem cells to assess neurodevelopmental toxicants and CNS-active drugs |
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Developmet of a new reconstituted human corneal model to assess the ocular irritating test |
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Prevalidation study for testing the toxic effects of inhalable substances (gases) on human lung cells using an air/liquid culture technique |
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Use of in vivo bioluminescence imaging for the investigation of bacterial infection courses and heterologous gene expression of bacterial vectors with small groups of mice |
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Caco-2 adenocarcinoma on chicken embryos chorioallantoic membrane (CAM) as an alternative to mammalian models for preclinical tests of new cytostatic drug formulations |
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ARPE-19 retinal pigment epithelia cells as an in vitro model for the examination of light induced cell damage in the eye |
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Nanotechnology and contact allergy |
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Training the animal doctor: Caring as a clinical skill |
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Dynamic 3D in vitro intestinal test system |
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Confrontation cultures of embryonic stem cell-derived embryoid bodies and multicellular tumour spheroids: a novel in vitro model for the study of tumour-induced angiogenesis |
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Assessment of corneal surface impairment and early signs of eye irritation on reconstructed human corneal epithelium |
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Swiss court bans work on Macaque brains |
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Development of an in vitro cultivation system for the haemotrophic bacterium Mycoplasma Suis |
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Bringing toxicology into the 21st century: A global call to action |
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A simple and inexpensive in vitro model to study the effects of hypoxia on pulmonary epithealial and microvascular endothelial cells |
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Novel test lung for real life supported simulation |
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Assessment of DNA oxidation by Nitroheterocyclic compounds using cultured YAC-1 cells |
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Influence of danger signals” on CD54 and CD86 marker expression in THP-1 cells - Improvement by HaCaT-Coculture |
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Non-Animal Approaches to Inhalation Toxicity Assessment: A Proposal for a Way Forward |
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Gene expression analysis in chemical-treated dendritic cells: Discriminating contact sensitisers and irritants employing the immune toxicity chip and a whole genome array |
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Opportunities and threats for animals during the implementation of REACH |
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Recommendations for the revision of Directive 86/609/EEC from the European animal protection movement |
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The continued need for a cruelty-free standard for cosmetics |
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Estimates for Worldwide Laboratory Animal Use |
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SkinEthic’ Reconstructed Human Epidermis (RHE) model: Development of an alternative method for skin irritation testing |
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Daphnia magna as alternative bioobject in ecotoxicology |
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Surface modification influences the in vitro toxicity of gold nanoparticles in human alveolar type-II cell lines |
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The Perspectives of integration of humane education in Armenia |
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Quantitation of sensitizing potential by the loose-fit coculture-based sensitization assay (LCSA) in comparison with LLNA-data |
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Metabolism studies of the Phenion® full thickness skin model as compared to other in vitro models and human native skin |
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Cell based assay for label-free, long-term investigation of living cells as alternative testing method for toxicity |
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Application of an intelligent testing strategy to the US EPA Endocrine Disruptor Screening Program |
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Progress in sharing data from repeated dose toxicity studies |
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Development of an in vitro test system for developmental neurotoxicity |
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A human corneal model for the prediction of eye irritation: progress report |
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