Serum Free Cell Culture Media - Updated Product Guide 1/2004-05
E. Falkner, H. Appl, C. Eder, K. Macfelda, U. Losert, H. Schöffl, W. Pfaller
The cultivation of cells in vitro has become an important tool for biomedical research and recombinant production purposes. The supplementation of mammalian cell culture media with sera (-components) of animal origin remains still standard, providing for e.g. necessary nutrition, shear protection, growth factors and cytokines. Because of undefined composition, risk of contaminations, cost factor and also animal welfare considerations concerning the production of sera, the switch to serum free alternatives is promoted by regulatory authorities, industry and the research community in general. To support this trend and to help save one of scientist´s most valuable resources - time - a catalogue was compiled of commercially available formulations, structured for their specified fields of application, i. e. cells/tissues/cell lines and manufacturers. This document provides an overview of the range of commercially available serum-free media for cell culture, and has been compiled by zet, Centre for Alternative and Complementary Methods to Animal Testing, and the Core Unit for Biomedical Research, Medical University Vienna working together to advance the replacement of animal experiments. We would welcome feedback on ways of encouraging and extending the use of serum-free media.
PLEASE NOTE: The information in this document has been compiled mainly from details provided by companies selling cell culture media on the Worldwide Web. The document is not intended to be comprehensive, and although every effort has been made to ensure the details contained are correct the authors cannot be held responsible for any inaccuracies. For full up-to-date information on any product in this table it is recommended that you contact the manufacturer or supplier directly.
This work was funded by the local government of Upper Austria and performed by zet – Centre for Alternative and Complementary Methods to Animal Testing, Linz, Austria, in cooperation with the Core Unit for Biomedical Research, Medical University Vienna, Austria.